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Have you heard of NAD+?

Nicotinamide adenine dinucleotide is a long name for something that is naturally occurring in your body. That's why most of us have heard about taking NAD+. But why?

NAD+ is in every cell of the human body? That' right, it's a vital part of life that declines as we age. NAD+ is classified as a coenzyme. A coenzyme is a substance that works with an enzyme to initiate or aid the function of the enzyme. So essentially NAD+ helps your body function correctly. Low level of NAD+ can result in many different health problems.

Low NAD+ levels have been linked to diabetes, heart disease, vascular dysfunction, ischemic brain injury, Alzheimer’s, and vision loss.

The benefits of NAD+ are:

  • Anti-aging

  • Increased energy

  • Improved cognition

  • Increased metabolism

  • Combats depression and anxiety

  • Increased cellular function

  • Repair damaged DNA

  • Increased glutathione levels (which neutralizes harmful substances in our body)

NAD+ acts as fuel for many key biological processes, such as:

  • Converting food into energy

  • Repairing damaged DNA

  • Fortifying cells’ defense systems

  • Setting your body’s internal clock or circadian rhythm

Supplementing NAD+ can be done through an IV infusion or by mouth. The results are usually more noticeable when using the IV route. Almost anytime a medication can bypass the digestive tract is a benefit. The levels in the body are higher quicker and results are felt sooner.

Other uses for NAD+ which are not fully understood, but have been used with success:

  • Drug dependency

  • Chronic fatigue

  • Pain management

  • Autoimmune disease

The only person who should avoid taking NAD+ are mothers who are pregnant or breastfeeding. This is mainly due to the lack of research of the effects of NAD+ around childbirth.

When supplementing NAD+, any excess NAD+ or its metabolites are excreted in urine. This keeps the levels safe in most people.

Call us to schedule a time to see if NAD+ supplementation is right for you. (828) 761-1710

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Noah Clifford
Noah Clifford
Aug 23, 2023

NAD+ is favorably involved in maintaining telomeric domains, repairing DNA damage, and potentially improving insulin sensitization, it's importance in health is undeniable. That being said, the bioavailability of barebones NAD+ supplements is extremely low (see link below). It may be better to take Tryptophan supplements along with precursors to NAD which are more bioavailable such as NMN and NR.

Pharmacology and Potential Implications of Nicotinamide Adenine Dinucleotide Precursors - PMC (

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